PolarCath - The "Cool" Peripheral Dilatation System
The PolarCath Balloon Dilatation System is an important component in my treatment algorithm for peripheral arterial disease.  Its unique and differentiated mechanism of action is critical in treating my patients
Dr. Bruce Ourieff - Interventional Cardiologist
Proposed Mechanism of Action
Cryoplasty is the peripheral angioplasty balloon offering the unique science of cryogenic cooling to treat peripheral vascular disease
  • Apoptosis - This non-inflammatory mechanism reduces vascular smooth muscle cells that have been shown to contribute to neo-intimal formation
  • Altered Plaque Response - Cryotherapy may limit vessel trauma and reduce the frequency of flow limiting dissections by promoting a more uniform response to dilatation
  • Reduced Elastic Recoil - Pre-clinical studies have shown that cryotherapy temporarily alters elastin fibers, which can reduce arterial wall elasticity
Indications for Use
The PolarCath Peripheral Dilatation System's intended use is for the dilatation of stenoses in the peripheral vasculature (iliac, femoral, popliteal, infrapopliteal, renal, and subclavian arteries) and for the treatment of obstructive lesions of polytetrafluoroethylene (PTFE) access grafts or native arteriovenous dialysis fistulae.  The PolarCath Peripheral Dilatation System is also indicated for post-deployed stent expansion of self-expanding peripheral vascular stents.